Evidence supporting the use of: Blue cohosh
For the body system: Muscles
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Blue Cohosh (Caulophyllum thalictroides) has a long-standing history of use in traditional herbal medicine, particularly among Native American and early North American settlers. It has been primarily used for its effects on the female reproductive system, especially to promote labor and ease childbirth. In this context, Blue Cohosh is thought to act as a uterine tonic, supporting the smooth muscles of the uterus to facilitate contractions and delivery. The use of Blue Cohosh for general muscle support outside of its effects on uterine muscle is less well-documented, but its reputation as a “parturient” or childbirth aid indirectly ties it to the muscular system through uterine muscle stimulation.
Despite its traditional use, modern scientific validation for Blue Cohosh’s efficacy and safety is limited. Some laboratory studies have identified compounds in Blue Cohosh (such as alkaloids and saponins) with potential uterine stimulant activity. However, robust clinical trials in humans are lacking, and concerns have been raised about possible toxicity, including cardiovascular risks for both mother and infant. Therefore, while there is traditional justification for its use to support uterine muscle function, the overall evidence is weak, and its application to broader muscular support is not well-supported by either traditional or scientific literature.
Other ingredients that support Muscles
Acetyl L-carnitineAcetylcholine
adenosine 5-triphosphate disodium (ATP)
Adenosine triphosphate (ATP)
Algae
Algal protein
Alpha hydroxyisocaproic acid
alpha-ketoglutarate (AKG)
Alpha-ketoisocaproic acid
amino acids
AMP-activated protein kinase (AMPK)
animal protein
animal Tissue
Anserina
antler
arachidonic acid
arginine alpha ketoglutarate
Arginine alpha-ketoisocaproate
Arginine aspartate
arginine creatine
Arginine malate
Arginine nitrate
Arginine silicate
arnica
ashwagandha
astaxanthin
avocado
ba ji tian
banana
BCAA
bee products
beef
Beef liver
Beef Protein
beet
beta-alanine
beta-hydroxybutyrate
bicarbonate
Biopeptide
black galingale
black ginger
black gram
Black willow
blue cohosh
bovine
bovine liver
bovine protein
branched-chain amino acids
bromelain
brown rice protein
C-phycocyanin
caffeine
calcium
camphor oil
cardarine
Carnosine
casein
Cetylated Fatty Acids
cherry
chia seed
chickpea protein
Chinese mountain ant
chloride
chuchuhuasi
citrate malate
coca
Coconut Water
coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
cramp bark
creatine
creatine monohydrate
Curcuma
Curcuminoid
Cyanotis arachnoides
Cyanotis vaga
Cyathula
d-alpha tocopherol
D-Ribose
date
deer velvet
devil's claw
dextrose
Dimethyl sulfoxide (DMSO)
Dipeptide
Dipsacus
DL-Methionine
dong quai root
ecdysteroids
ecdysterone
egg
Egg protein
electrolytes blend (proprietary)
elk antler
emu oil
epicatechin
epistane
Erythrina
essential oil blend
Ethyl-Alpha-Guanido-Methyl-Ethanoate
eucommia
Eurycoma Longifolia
fatty acids
fibroblast growth factor
fish
fish protein
forskohlii root
Ginsenosides
glucose
Glutamine
Glycerol
Glycine
Glycocyamine
GMS-ribose
guanidinoacetic acid
guanidinopropionic acid (GPA )
guelder rose
Haematococcus pluvialis
hairy arnica
herbal blend (proprietary)
HMB hydroxymethylbutyrate
hydroxymethylbutyrate
icariin
Iporuru
iron
Isoleucine
isomaltulose
kale
ketosterones
L-alanine
L-alanyl-L-glutamine
L-arginine
l-carnitine
L-carnosine
L-citrulline
L-glutamine
L-glycine
l-isoleucine
L-leucine
L-ornithine
L-proline
L-taurine
L-threonine
L-valine
lactalbumin
Lavandin
Legume protein
Lentein
Lentil
leucine alpha-ketoglutarate
lipids
magnesium
malic acid
maral root
Marine protein
Marjoram
Maslinic acid
Menthol oil
Methylsulfonylmethane (MSM)
Methylxanthine
Milk
Milk Protein
Mineral ascorbate
Mineral blend
NADH
nicotinamide riboside
Ornithine
ornithine alpha-ketoglutarate
Pea
Peppermint
Peptides
Phosphatidic Acid
Phosphocreatine
phosphorus
phytocannabinoids
Phytoecdysteroid
Plankton
polyphenols
potash
potassium
Propionyl-L-Carnitine
protein
proteolytic enzymes
Puerain
pyruvate
Qin Jiao
quinoa
Quinoa Protein
Rhaponticum
rhizome
ribose
rue
Safed musli
Salmon Oil
salt
Shilajit
Sida cordifolia
siler root
solomon's seal
Soy Protein
soybean
specialized pro-resolving mediators (SPMs)
spinach
spirulina
squawvine
suma
Taurine
Taxillus sutchuenensis
Terpenoids
Tongkat ali
trace minerals
Tribulus Terrestris
Trichopus zeylanicus
Turkesterone
turmeric
Tynanthus panurensis
ubiquinol
Urolithin A
Ursolic Acid
Vegetable Protein
Viburnum
vitamin B
vitamin C
vitamin D
vitamin D3
Watermelon
wheat germ
Whey protein
white willow
Wintergreen
Withanolides
Wood betony
β-nicotinamide mononucleotide (NMN)
Other body systems supported by blue cohosh
Female Reproductive SystemGlandular System
Muscles
Reproductive System
Uterus
Vagina
