Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Hydrolyzed beef collagen is sometimes marketed as a supplement to support muscle tone, primarily due to its high content of amino acids like glycine, proline, and hydroxyproline. Scientific evidence supporting its use for improving muscle tone (specifically addressing lack of muscle tone or hypotonia) is limited but emerging. Most research on collagen supplementation focuses on its benefits for skin, joint health, and, to a lesser extent, muscle mass in older adults. A small number of studies have shown that collagen peptide supplementation, when combined with resistance training, may improve muscle mass and strength in elderly men compared to placebo. For example, a 2015 randomized controlled trial by Zdzieblik et al. found that older men who took collagen peptides alongside resistance training gained more fat-free mass and muscle strength than those who used a placebo. However, these studies are few, often use small sample sizes, and typically involve specific populations (such as older adults with sarcopenia), not individuals with clinical hypotonia or general lack of muscle tone. There is currently inadequate evidence to support hydrolyzed beef collagen as a primary intervention for muscle tone deficiencies, especially outside the context of resistance exercise. Thus, while there is some scientific basis for its adjunctive role in muscle health, the overall evidence for its effectiveness in treating lack of muscle tone is weak.

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