Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Creatine is widely studied and used for supporting muscle function, particularly in relation to muscle strength, mass, and tone. Scientific validation comes from numerous randomized controlled trials and meta-analyses showing that creatine supplementation increases phosphocreatine stores in muscle, which enhances ATP regeneration during short, high-intensity exercise. This effect leads to improved muscle performance, increased strength, and, over time, greater gains in muscle mass and tone, especially when combined with resistance training.

Creatine supplementation is not only used by athletes but also studied in clinical populations experiencing muscle atrophy or weakness, such as older adults (sarcopenia), patients with muscular dystrophy, and those recovering from immobilization. Research shows that creatine can help mitigate muscle loss, improve physical performance, and enhance rehabilitation outcomes in these groups.

While creatine is not a direct treatment for neurological or systemic causes of hypotonia (pathological lack of muscle tone), it is effective in addressing muscle weakness and poor tone related to disuse, aging, or certain muscle diseases. Safety studies indicate that creatine is generally well-tolerated at recommended doses. Overall, its use to support and improve muscle tone is well-supported by scientific data, particularly when muscle tone loss is related to disuse or aging rather than neurological origins.

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