Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Bee venom therapy (BVT) has a traditional basis for use in multiple sclerosis (MS), stemming from historical folk medicine practices and apitherapy—a branch of alternative medicine that utilizes bee products. Proponents of BVT claim that the anti-inflammatory and immunomodulatory components of bee venom, particularly melittin, may benefit autoimmune conditions like MS. However, scientific validation for these claims is limited. Some animal studies and small human trials have investigated bee venom’s effects on immune function and inflammation, but results are inconclusive or show minimal benefit. The American Academy of Neurology and National Multiple Sclerosis Society do not endorse bee venom therapy due to insufficient evidence of efficacy and concerns about safety, including potential allergic reactions and anaphylaxis. Most contemporary clinical trials have not demonstrated significant or consistent improvements in MS symptoms or progression with BVT compared to placebo. Thus, while the use of bee venom in MS is rooted in tradition and anecdotal reports, robust scientific evidence supporting its effectiveness is lacking.

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