Evidence supporting the use of: Riboflavin (vitamin B2)
For the body system: Mucus Membranes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Riboflavin (vitamin B2) is scientifically validated to support the health of mucus membranes. Riboflavin is an essential water-soluble B vitamin that functions primarily as a precursor to the flavin coenzymes FMN and FAD, which are involved in numerous oxidation-reduction (redox) reactions in the body. Its role in maintaining the integrity of epithelial tissues, including mucus membranes, is well established. Riboflavin deficiency, known as ariboflavinosis, presents clinically with symptoms such as cheilosis (cracking at the corners of the mouth), glossitis (inflammation of the tongue), and dermatitis—conditions that directly reflect compromised mucus membrane and skin health. These symptoms have been documented in both observational studies and controlled depletion-repletion studies in humans. Furthermore, the European Food Safety Authority (EFSA) and other regulatory agencies recognize the contribution of riboflavin to the maintenance of normal mucus membranes as a substantiated health claim based on established scientific understanding. Supplementation or adequate dietary intake of riboflavin reverses deficiency symptoms and supports normal tissue structure and function. Thus, riboflavin’s use in supporting mucus membrane health is based on clear biochemical rationale, clinical evidence of deficiency syndromes, and regulatory consensus.

More about riboflavin (vitamin B2)
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