Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Devil's Club (Oplopanax horridus) has been used traditionally by Indigenous peoples of the Pacific Northwest for a variety of ailments, including those affecting the respiratory tract and mucus membranes. Ethnobotanical records indicate its use in teas, poultices, and smoke for treating colds, sore throats, tuberculosis, and other respiratory complaints. These applications have often involved supporting mucus membrane health and alleviating irritation or inflammation. However, scientific research specifically validating these traditional uses is limited. While some laboratory studies have identified antimicrobial and anti-inflammatory properties in Devil's Club extracts, there is insufficient clinical research directly linking Devil's Club to measurable benefits in mucus membrane health in humans. Thus, while the tradition is strong and the rationale plausible based on observed properties, the evidence base remains modest, with most support coming from ethnobotanical traditions rather than rigorous scientific trials.

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