Colostrum, the first form of milk produced by mammals immediately following delivery, has been investigated for its potential to support the health of mucus membranes, particularly those of the gastrointestinal tract. Scientific evidence indicates that colostrum is rich in immunoglobulins (notably IgA), lactoferrin, growth factors, and other bioactive compounds that may help protect and repair mucosal surfaces. Several clinical studies have examined bovine colostrum's effect on gut health. For example, randomized controlled trials have shown that bovine colostrum supplementation can help maintain gut barrier integrity and reduce intestinal permeability, particularly in athletes exposed to physical stress or in individuals with gastrointestinal conditions such as NSAID-induced gut injury (Playford et al., 2000). Other studies suggest colostrum may reduce the severity and duration of infectious diarrhea, and support recovery in patients with inflammatory bowel conditions.

The majority of evidence focuses on the gastrointestinal mucus membranes, with more limited data on other mucosal surfaces. While more research is needed to establish optimal doses and long-term safety, current findings provide a moderate level of scientific validation for the use of colostrum to support mucus membrane health, particularly in the gut. Therefore, the evidence is rated as 3 out of 5, reflecting promising but not conclusive scientific support.