Evidence supporting the use of: Calendula
For the body system: Mucus Membranes
Synopsis
Source of validity: Traditional
Rating (out of 5): 3
Calendula (Calendula officinalis), commonly known as marigold, has a long history of traditional use in supporting the health of mucus membranes, particularly in the mouth, throat, and digestive tract. Herbalists have used calendula preparations—such as teas, tinctures, and topical applications—for their purported soothing and healing effects on inflamed or irritated mucosal tissues. Folklore and traditional European herbal medicine records cite calendula as a remedy for sore throats, mouth ulcers, and gastritis, attributing its benefits to its anti-inflammatory, antimicrobial, and tissue-healing properties.
Scientific studies investigating calendula focus primarily on its wound-healing and anti-inflammatory effects, with some in vitro and animal research suggesting that calendula extracts can modulate inflammation and promote tissue repair. However, direct clinical evidence supporting calendula’s use specifically for mucus membrane conditions in humans is limited. A handful of small studies and case reports suggest benefits for oral mucositis (inflammation of the mouth lining) in cancer patients, but robust, large-scale clinical trials are lacking. Overall, while there is strong traditional support and some preliminary scientific rationale, the evidence base is not comprehensive.
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basil
bayberry
beta-carotene
bilberry
bisabolol
blackberry
broccoli
ceramides
chamomile
citrus bioflavonoids
clove
coating
colostrum
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dandelion
fruit and vegetable blend (proprietary)
glehnia root
glycerin
goldenseal
onion
horseradish
hypromellose
l-cysteine
l-threonine
lactobacillus crispatus
lactobacillus jensenii
lactobacillus salivarius
lactoferrin
lactoperoxidase
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licorice root
marshmallow
methylmethionine sulfonium chloride (vitamin U)
mint
mixed carotenoids
mucin
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nettle
niacin (vitamin B3)
okra
olive
omega-7 fatty acids
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pear
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plantain
platycodon root
prebiotic blend (proprietary)
raspberry
riboflavin (vitamin B2)
rose oil
sage
slippery elm bark
sorbitol
thyme
vitamin A
vitamin C
vitamin E
water
xylitol
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zinc
yellow root
boneset
mullein
chickweed
cardamom
lobelia
capsicum
mugwort
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tylophora
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cayenne pepper
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Bethroot
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Bioflavonoids
Butterbur
Bee products
Borage
Balloon Flower
Belamcanda
Bird's nest
Calendula
Colloidal Silver
Cod Liver Oil
Carvacrol
Citrus
Cineole
Cornflower
Cajuput
Cantaloupe
Catechu
Centipeda
Cistus
Cubeb
Cowslip
Cranesbill
Carotene (unspecified)
Chekiang Fritillary
Collinsonia
Chondrus
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English Horsemint
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Echinacea
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Other body systems supported by Calendula
Digestive SystemGastrointestinal Tract
Gums
Immune System
Intestinal System
Liver
Lymphatics
Mucus Membranes
Skin
Vagina