Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Akkermansia muciniphila is a gut bacterium that has been the focus of considerable scientific interest due to its unique ability to degrade mucin, the main component of the mucus layer that lines the gut mucosa. Multiple preclinical studies in mice and in vitro research have shown that A. muciniphila interacts directly with the mucus layer, stimulating its renewal and enhancing its thickness. This is important for maintaining the integrity of the intestinal barrier and supporting overall mucosal health. Several studies have reported that the presence of A. muciniphila is associated with improved gut barrier function and reduced inflammation, and that its abundance is inversely correlated with metabolic disorders such as obesity and type 2 diabetes (Everard et al., 2013; Derrien et al., 2017).

Early human trials are limited but promising; oral supplementation with pasteurized A. muciniphila has been shown to improve some metabolic parameters and markers of gut barrier function in overweight and obese individuals (Depommier et al., 2019). However, most of the direct evidence for supporting mucus membranes comes from animal and mechanistic studies rather than large-scale human clinical trials. In summary, there is a moderate level of scientific evidence (primarily preclinical and early clinical) supporting the use of Akkermansia muciniphila for supporting mucus membrane function, particularly in the gut.

More about akkermansia muciniphila
More about Mucus Membranes

Other ingredients that support Mucus Membranes

Other body systems supported by akkermansia muciniphila

Products containing akkermansia muciniphila