Evidence supporting the use of: Maca
For the health condition: Mood Swings
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Maca (Lepidium meyenii), a root native to the Andes, has a long history of traditional use in Peruvian folk medicine for enhancing vitality, fertility, and overall well-being. Among its purported benefits, maca is often used to support mood and emotional balance, particularly during periods of hormonal fluctuation such as menopause or PMS. The traditional rationale is partly based on maca’s adaptogenic properties—herbs believed to help the body resist physical, chemical, and biological stressors—which may indirectly impact mood.
While there is a growing body of preliminary scientific research investigating maca’s effects on mood, the evidence remains limited. Several small clinical studies have reported that maca supplementation may help reduce symptoms of anxiety and depression, particularly in menopausal women. For example, a 2008 study published in Menopause found that postmenopausal women who took maca experienced reduced psychological symptoms, including anxiety and depression, compared to placebo. However, these studies are often small-scale, short-term, and sometimes lack rigorous controls.
Overall, the traditional use of maca for mood swings is well-established in indigenous Andean cultures, and some initial scientific findings are promising. However, the strength of evidence is moderate at best (rated 2 out of 5), and more robust clinical trials are needed to conclusively determine maca’s efficacy for mood regulation.
Other ingredients used for Mood Swings
5-Hydroxytryptophan (5-HTP)ashwagandha
beta caryophyllene
bifidobacterium longum
black tea
chaste tree
turmeric
l-theanine
l-tryptophan
l-tyrosine
lactobacillus casei
lactobacillus reuteri
licorice root
lion's mane
lithium orotate
maca
magnesium
matcha
Acetyl-L-Tyrosine
pregnenolone
reishi mushroom
relora® (proprietary)
rhodiola
vitamin B12
vitamin B6
vitamin D
zinc
St. John's Wort
yerba mate
cocoa
Bifidobacteria
bacoside
Chocolate
Devil's Club
Rose
Other health conditions supported by maca
Adrenal FatigueAmenorrhea
Anemia
Anxiety
Athletic and Exercise Aids
Depression
Diabetes
Energy (lack of)
Erectile Dysfunction
Fatigue
Hot Flashes
Infertility
Insomnia
Irritability
Memory and Brain Function
Menopause
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Miscarriage (prevention)
Mood Swings
Muscle Tone (lack of)
Nervous Exhaustion
Nocturnal Emission
Osteoporosis
PMS (general)
Progesterone (low)
Puberty (hormone balancer)
Sex Drive (low)
Stress
Testosterone (low)