Evidence supporting the use of: Mushrooms
For the body system: Mitochondria
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Mushrooms, particularly medicinal varieties such as Cordyceps, Reishi (Ganoderma lucidum), and Lion’s Mane (Hericium erinaceus), have garnered increasing scientific interest for their potential to support mitochondrial health. Several studies have focused on Cordyceps, which contains bioactive compounds like cordycepin and polysaccharides. Preclinical research indicates that Cordyceps can enhance cellular ATP production, improve mitochondrial efficiency, and reduce oxidative stress in animal models (Qi et al., 2015). Similarly, antioxidants found in Reishi and other mushrooms may protect mitochondrial membranes from oxidative damage, although most evidence is based on cell culture and animal studies rather than robust human trials.
While traditional use of these mushrooms in East Asian medicine includes claims of increased vitality and endurance, modern research is beginning to clarify molecular mechanisms by which mushroom extracts might support energy metabolism and mitochondrial function. However, high-quality clinical trials in humans are limited, and findings are often preliminary. Thus, while there is a scientific rationale and some supporting evidence—mainly from preclinical studies—the strength of clinical evidence is moderate at best.
Other ingredients that support Mitochondria
7-Keto-DHEAacetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
bovine liver
caffeine
catechins
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine monohydrate
d-alpha tocopherol
epigallocatechin gallate (EGCG)
fisetin
fish oil
flavonols
fructose
fruit and vegetable blend (proprietary)
glycerophosphocholine (GPC)
gooseberry
grape
greens blend (proprietary)
hesperetin
knotweed
krill oil
l-carnitine
l-carnosine
l-citrulline
l-glutathione
l-glycine
l-taurine
lentinula edodes mycelia
linoleic acid (LA)
liquid liver fractions
luteolin
mackerel
magnesium
maitake mushroom
malic acid
maltodextrin
maltose
manganese
maqui berry
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
trans-geranylgeraniol
trans-pterostilbene
tributyrin
turkey tail mushroom
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
water
watermelon
β-nicotinamide mononucleotide (NMN)
lingzhi
cistanche
ganoderma
electrolytes blend (proprietary)
polyphenols
trace minerals
fulvic acid
goji berry
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
thyroid substance
ashitaba
1,3,7-Trimethylpurine-2,6-dione
5-Aminoimidazole-4-Carboxamide Ribonucleotide
Alpha polylactate
Apigenin
Alpha-Lipoic Acid
Ampelopsin
adenosine triphosphate (ATP)
Animal protein
Beta-hydroxybutyrate
Beef liver
berry
Caffeic Acid
Centrophenoxine
Camellia sinensis
Cardarine
Cocarboxylase
Capsinoids
Coenzyme A
Cardiolipin
Cyanidin
Capsiate
Chocolate
Creatine
C-Phycocyanin
Dihydrolipoic Acid
D-Ribose
Eriocitrin
Ergothioneine
Ketone Salts
Other body systems supported by Mushrooms
Adrenal CortexAdrenal Glands
Arteries
Blood
Brain
Circulatory System
Digestive System
Gastrointestinal Tract
Glandular System
Heart
Hepatic System
Hypothalamus
Immune System
Intestinal System
Kidneys
Large Intestines (Colon)
Liver
Lungs
Lymphatics
Mitochondria
Nerves
Respiratory System
Skin
Spleen
Stomach
Thymus