Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Krill oil is a marine oil supplement rich in omega-3 fatty acids, particularly EPA and DHA, which are known to play key roles in cellular health. While there is scientific interest in the potential of krill oil to support mitochondrial function, the evidence is still emerging and not robust. Some preclinical studies suggest that omega-3s can help improve mitochondrial efficiency and reduce oxidative stress, both of which are important for optimal mitochondrial function. Krill oil is unique compared to fish oil because its omega-3s are primarily in phospholipid form, which may enhance cellular uptake, including in mitochondria.

However, direct studies on krill oil specifically enhancing mitochondrial function in humans are limited. Most research has evaluated general cellular health or cardiovascular markers, with only a few animal or in vitro studies showing benefits such as increased mitochondrial respiration or reduced mitochondrial oxidative damage. Therefore, while there is a plausible scientific rationale and some preliminary evidence, the use of krill oil to support the mitochondrial system is not yet strongly validated by large-scale clinical trials.

In summary, krill oil’s support for mitochondrial health is based on early-stage scientific evidence, much of it extrapolated from general omega-3 research, and should be considered promising but not definitive.

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Nature's Sunshine Krill Oil (With Vitamin K2)