Evidence supporting the use of: Safflower
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Safflower (Carthamus tinctorius) has a long history of use in traditional medicine, particularly in Chinese and Middle Eastern practices. In Traditional Chinese Medicine (TCM), safflower is known as "Hong Hua" and is used to invigorate blood circulation and alleviate pain. There are historical indications that safflower preparations were sometimes used to treat headaches, which could include migraines, based on the TCM principle of improving blood flow to relieve pain and stagnation. However, these uses are not specific to migraine as defined in modern medicine, but rather to general headache or pain relief. There is minimal to no scientific evidence from clinical studies supporting safflower’s effectiveness specifically for migraine. No high-quality randomized controlled trials or systematic reviews substantiate its use for this condition in the biomedical literature. Instead, its application for migraine remains grounded in traditional practices, with anecdotal and historical usage rather than robust scientific validation. Therefore, while safflower is sometimes referenced in traditional systems for headache or pain, the evidence for its effectiveness in treating or supporting migraine is weak and not scientifically established.

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