Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Mesua, commonly known as Nagakesara or Mesua ferrea, is traditionally used in Ayurveda and other traditional medicinal systems for a variety of ailments, including headaches and migraines. The plant is esteemed for its anti-inflammatory, analgesic, and calming properties, which are believed to alleviate pain and discomfort associated with migraines. References to Mesua’s use for headaches can be found in classical Ayurvedic texts, where it is often included in polyherbal formulations designed to address neurological and vascular complaints. However, the evidence supporting this use is primarily anecdotal and rooted in historical practice, rather than rigorous scientific validation. Modern scientific studies directly evaluating Mesua’s efficacy for migraine are lacking, and most available research focuses on its general pharmacological properties, such as antioxidant and anti-inflammatory effects. While these actions could theoretically contribute to migraine relief, there is no high-quality clinical evidence specifically confirming its effectiveness for this condition. Therefore, the use of Mesua for migraine relief is justified by tradition, with limited evidence from preclinical studies and no substantial clinical trials to date.

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