Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Citrus reticulata (mandarin orange) has a long history of use in traditional Chinese and other Asian medical systems, primarily for digestive and respiratory ailments. In traditional medicine, its dried peel ("Chen Pi") is valued for its ability to move qi, resolve phlegm, and support digestion. There is limited traditional mention of its use specifically for migraine headaches. Some herbal formulations that include Citrus reticulata may be used for "head pain" or symptoms that could overlap with modern concepts of migraine, but the connection is indirect and not well-documented.

From a scientific perspective, there is currently no robust clinical evidence supporting the use of Citrus reticulata or its extracts in the prevention or treatment of migraine. Studies have focused on its anti-inflammatory, antioxidant, and neuroprotective effects, but these have not been directly linked to migraine relief in humans. Some animal and in vitro studies suggest potential neuroprotective properties of certain flavonoids in Citrus reticulata, but this is insufficient to support its use for migraine in clinical practice.

In summary, the use of Citrus reticulata for migraine is based on tradition rather than scientific evidence, and even in traditional systems, its application for migraine is not primary or well-established.

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