Evidence supporting the use of: Black Seed Oil
For the health condition: Migraine
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Black seed oil, derived from Nigella sativa, has a long history of use in traditional medicine systems, including those of the Middle East, North Africa, and South Asia. In these traditions, black seed oil has been used to treat a variety of ailments, including headaches and migraines. Some sources in traditional Islamic medicine, for example, recommend black seed (often referred to as "the blessed seed") for general pain relief and neurological complaints.
However, scientific evidence supporting the use of black seed oil specifically for migraine is limited. A few small, preliminary clinical studies and animal models suggest that Nigella sativa may have anti-inflammatory, antioxidant, and analgesic properties, which could theoretically be beneficial in migraine management. For instance, a 2017 randomized controlled trial published in Phytotherapy Research suggested that black seed oil capsules reduced the frequency and severity of migraine attacks in a small group of patients. However, the study had limitations, including small sample size and short duration. Other studies have evaluated black seed oil’s general pain-relieving properties, but not specifically in migraine populations.
Overall, while there is a foundation in traditional use for headache and migraine, high-quality scientific evidence remains limited, and more rigorous studies are needed to confirm efficacy and safety for this specific indication.
Other ingredients used for Migraine
5-Hydroxytryptophan (5-HTP)alpha-linolenic acid (ALA)
ashwagandha
bergamot
beta caryophyllene
black tea
Indian frankincense
bupleurum falcatum
Chinese salvia root
coenzyme Q10 (CoQ10)
turmeric
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
feverfew
fish oil
ginger
ginkgo biloba
gooseberry
gotu kola
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
luteolin
magnesium
melatonin
moringa
niacin (vitamin B3)
omega-3 fatty acids
Peppermint
phytocannabinoids
pine bark
purple butterbur root
riboflavin (vitamin B2)
specialized pro-resolving mediators (SPMs)
Almond fruit
ubiquinol
valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
zinc
atractylodes
blackboard tree
swertia
Szechuan lovage
chrysanthemum
soursop
1,3,7-Trimethylpurine-2,6-dione
5-methyltetrahydrofolate glucosamine
Apple Cider Vinegar
Albizia
Alpha-Lipoic Acid
Atractylone
Betony
Black Seed
Baikal Skullcap
Beta-hydroxybutyrate
Blepharis
Balsam
Banyan
Brahmi
Butterbur
Bifidobacteria
Black Hellebore
Chinese Silkvine
Crocin
Creatine
Cannabidiol
Corydalis
Carthamus
cola nut
Docosahexaenoic Acid
Danshen
Eicosapentaenoic Acid
Folic Acid
Flavin mononucleotide
Ficus religiosa
Fish
Flavanones
Ficus simplicissima
Frankincense
Goldthread
Gelsemium
Ginkgolides
Ginkgoside
Hellebore
iridoids
Ketone Salts
Kuding tea
lemon balm
Lesser speargrass
Little ironweed
Linalool
Mesua
Methylxanthine
Meadowsweet
Nardostachys
Night jessamine
Osthole
Puerarin
Petasines
Phthalides
Paeoniflorin
Pycnogenol
Polygonum
Palmitoylethanolamide (PEA)
Rue
Rubus
Rauvolfia
Rubiaceae
Spikenard
Sensitive Plant
Salmon Oil
Sandalwood
Scabrous Gentian
Uncaria
Withanolides
Xanthine
Xanthophyll
Xanthone
Yuzu
Zingerone
Other health conditions supported by Black Seed Oil
AcneAllergies (respiratory)
Anemia
Antibiotics (alternatives to)
Anxiety
Arthritis
Asthma
Backache
Boils
Bronchitis
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Colds (antiviral)
Colds (general)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Conjunctivitis
Constipation (adults)
Cuts
Depression
Dermatitis
Diabetes
Diarrhea
Digestion (poor)
Eczema
Emphysema
Fatigue
Fever
Fungal Infections
Gastritis
Gingivitis
Gout
Hair (loss or thinning)
Headache (general)
Headache (sinus)
Headache (tension)
Heart (weakness)
Hepatitis
Herpes
Hypertension
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Insomnia
Jaundice (adults)
Liver Detoxification
Lupus
Malaria
Migraine