Evidence supporting the use of: Black Hellebore
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Black Hellebore (Helleborus niger) has a long history of use in traditional European herbal medicine, including some historical references to its application for neurological complaints such as headaches and migraine-like symptoms. Ancient Greek and Roman physicians, such as Hippocrates and Dioscorides, mentioned hellebore as a remedy for various ailments, including what might now be classified as migraine or severe headaches. However, these references are broad, and the use of Black Hellebore was often associated with its purgative and emetic effects, which were thought to expel "bad humors" from the body. Modern scientific research on Black Hellebore for migraine is lacking; there are no well-conducted clinical studies or pharmacological investigations confirming its efficacy or safety for this indication. In fact, Black Hellebore contains toxic compounds (such as helleborin and helleborein) that can cause serious side effects, including nausea, vomiting, cardiac disturbances, and even death if used improperly. Due to its toxicity and lack of modern evidence, Black Hellebore is not recommended for migraine treatment today. Its historical use is acknowledged, but scientific validation is absent, and its inclusion in some traditional formulas is based primarily on pre-modern medical theories rather than evidence-based practice.

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Other ingredients used for Migraine

5-Hydroxytryptophan (5-HTP)
alpha-linolenic acid (ALA)
ashwagandha
bergamot
beta caryophyllene
black tea
Indian frankincense
bupleurum falcatum
Chinese salvia root
coenzyme Q10 (CoQ10)
turmeric
curcumin
DHA (docosahexaenoic acid)
EPA (eicosapentaenoic acid)
feverfew
fish oil
ginger
ginkgo biloba
gooseberry
gotu kola
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
luteolin
magnesium
Melatonin
Moringa
Niacin (vitamin B3)
omega-3 fatty acids
Peppermint
phytocannabinoids
pine bark
purple butterbur root
riboflavin (vitamin B2)
specialized pro-resolving mediators (SPMs)
Almond fruit
ubiquinol
Valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
Zinc
atractylodes
blackboard tree
Swertia
Szechuan lovage
chrysanthemum
soursop
1,3,7-Trimethylpurine-2,6-dione
5-methyltetrahydrofolate glucosamine
apple cider vinegar
Albizia
alpha-lipoic acid
atractylone
betony
black seed
Baikal Skullcap
beta-hydroxybutyrate
Blepharis
balsam
banyan
brahmi
butterbur
Bifidobacteria
Black Hellebore
Chinese silkvine
crocin
creatine
cannabidiol
Corydalis
Carthamus
cola nut
docosahexaenoic Acid
danshen
eicosapentaenoic acid
folic acid
flavin mononucleotide
Ficus religiosa
fish
flavanones
Ficus simplicissima
frankincense
goldthread
Gelsemium
ginkgolides
Ginkgoside
Hellebore
iridoids
ketone salts
kuding tea
lemon balm
Lesser speargrass
little ironweed
linalool
Mesua
Methylxanthine
Meadowsweet
Nardostachys
Night jessamine
Osthole
Puerarin
Petasines
Phthalides
paeoniflorin
Pycnogenol
Polygonum
Palmitoylethanolamide (PEA)
rue
Rubus
Rauvolfia
Rubiaceae
Spikenard
Sensitive Plant
Salmon Oil
Sandalwood
Scabrous Gentian
Uncaria
Withanolides
Xanthine
Xanthophyll
Xanthone
Yuzu
Zingerone

Products containing Black Hellebore

We currently have no products on Caring Sunshine that contain this ingredient.