Evidence supporting the use of: Whey protein
For the health condition: Metabolic Syndrome
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Whey protein has garnered scientific interest for its potential role in supporting and managing Metabolic Syndrome—a cluster of conditions including obesity, high blood pressure, dyslipidemia, and impaired glucose tolerance. Several randomized controlled trials and meta-analyses suggest that whey protein supplementation may help improve certain components of Metabolic Syndrome. Mechanistically, whey protein is rich in bioactive peptides and amino acids, which are believed to promote satiety, enhance insulin secretion, and improve glucose regulation. Some studies have shown that regular intake of whey protein can lead to modest reductions in body weight, waist circumference, and blood pressure in overweight or obese populations. Additionally, whey protein may improve lipid profiles by lowering total cholesterol and LDL cholesterol, while increasing HDL cholesterol.
However, the overall evidence is moderate, not robust. Some trials report only small or non-significant benefits, and results can be inconsistent depending on dosage, duration, and the population studied. The beneficial effects seem more pronounced when whey protein is part of a calorie-controlled diet and combined with physical activity.
In summary, while there is a scientific basis for whey protein use in supporting the management of Metabolic Syndrome—particularly for weight management, glycemic control, and improving cardiometabolic risk markers—the strength of evidence is moderate, and further large-scale, high-quality studies are needed to confirm its efficacy and establish optimal usage guidelines.
Other ingredients used for Metabolic Syndrome
7-hydroxymatairesinol (HMR)7-Keto-DHEA
Acai berry
Akkermansia muciniphila
algal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anchovies
anthocyanins
asparagus
bacillus subtilis
banaba
barley
berberine
beta-glucan
beta-sitosterol
Bifidobacterium longum
bitter melon
black garlic
blueberry
Brussel sprouts
butyrate triglyceride
campesterol
camu camu
canola oil
caterpillar mushroom
chia seed
chokeberry
chromium
cinnamon
conjugated linoleic acid (CLA)
turmeric
curcumin
DHA (docosahexaenoic acid)
DPA (docosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
fructooligosaccharides (FOS)
ginger
glucomannan
guar gum
hydroxycitric acid
inulin
krill oil
l-carnitine
Lactobacillus helveticus
licorice root
mackerel
maitake mushroom
maqui berry
Matcha
medium chain triglycerides (MCT)
Moringa
Naringin
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
quinoa
red yeast rice
reishi mushroom
resveratrol
rye
sardines
spirulina
tocotrienols
Trans-pterostilbene
Urolithin A
Vanadium
Vanadyl sulfate
vitamin C
vitamin D
wheat grass
Whey protein
xylooligosaccharides
Zinc
β-nicotinamide mononucleotide (NMN)
Algae
kidney beans
AMP-activated protein kinase (AMPK)
1-deoxynojirimycin
15,16-Dihydrotanshinone I
12-methylcarnosic acid
3-desoxy-7-KETO-DHEA
4-hydroxyisoleucine
5,7-Dimethoxyflavone
6-Paradol
Alpha Glucans
ankaflavin
apigenin
Aronia melanocarpa
Antrodia camphorata
Auricularia
antirrhinin
avocado
Ascophyllum nodosum
Acacetin
alpha-lipoic acid
astragaloside
anthocyanidins
ampelopsin
Alpha phytosterol
Algal protein
arabinoxylan
Alpha methyl tetradecylthioacetic acid
Arjunolic acid
Bifidobacterium adolescentis
beta-hydroxybutyrate
Blakeslea trispora
bean
betanin
Brazil nut
charantin
California chia
cardarine
cyanobacteria
capsinoids
cyanidin
chlorogenic acid
capsiate
Chitin-Glucan Complex
Calanus finmarchicus
crocetin
cynaropicrin
Cystoseira canariensis
corosolic acid
Crypthecodinium
carnosic acid
docosahexaenoic Acid
Dunaliella
dihydrocapsiate
dragon fruit
dihydrolipoic acid
D-Pinitol
diosgenin
ergothioneine
evodiamine
Ecklonia
fucosterol
Foxtail millet
fucoxanthin
flavanols
fructan
Ginsenosides
Glucan peptides
galactooligosaccharides
guanidinopropionic acid (GPA )
Guggulsterones
Glucoraphanin
garbanzo bean
Glucosinolates
hydroxytyrosol
isomaltulose
Isoalantolactone
Irvingia gabonensis
Konjac
Kamut
lipstatin
Legume protein
Lentil
lupin
Monacolin
Maslinic acid
mangiferin
Mulberroside A
Monounsaturated fat
Momordicosides
Naringenin
Neoeriocitrin
Nobiletin
oolong tea
Oligosaccharides
Oleoylethanolamide
Phycocyanin
pyrroloquinoline quinone
phlorizin
Phaeophyceae
Phytoplankton
polychitosamine
polysaccharides
Pinitol
Polydatin
punicalin
polyunsaturated fat
Pleurotus eryngii
pu-er tea
punicalagins
Palatinose
punicic acid
peanut
Pistachio
Rebaudioside
red miso
Schizochytrium Oil
Schizochytrium
Salmon Oil
Salidroside
Syringic acid
Salacia
Sesamolin
Sesamin
Sinensetin
Sulforaphane
Tagatose
Tetradecylthioacetic acid
Thylakoid
Tyrosol
Tangeretin
Tanshinone
Theaflavin
Theabrownin
Xanthohumol
Yacon
Other health conditions supported by Whey protein
Acquired Immune Deficiency SyndromeAthletic and Exercise Aids
Autoimmune Disorders
Body Building
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Cholesterol (high)
Convalescence
Depression
Diabetes
Energy (lack of)
Fatigue
Free Radical Damage
Inflammation
Liver Detoxification
Metabolic Syndrome
Muscle Tone (lack of)
Osteoporosis
Protein Digestion (poor)
Ulcers
Wasting
Weight Gain
Weight Loss
Wounds and Sores
Products containing Whey protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine Free Amino Acids