Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Tyrosol is a natural phenolic compound primarily found in olive oil and other olive products. Its use for metabolic syndrome is supported by emerging scientific evidence, though this evidence is still limited and largely preclinical. Tyrosol has been studied for its antioxidant, anti-inflammatory, and cardioprotective properties, which are relevant to the pathophysiology of metabolic syndrome—a cluster of conditions including obesity, insulin resistance, hypertension, and dyslipidemia. Animal studies have shown that tyrosol can improve lipid profiles, reduce oxidative stress, and ameliorate insulin resistance, all of which are beneficial in metabolic syndrome models (Pérez-Jiménez et al., 2016). Small human studies and epidemiological data suggest that diets rich in tyrosol-containing olive products (such as the Mediterranean diet) are associated with a lower risk of metabolic syndrome and its components. However, direct clinical trials using pure tyrosol supplementation in humans with metabolic syndrome are lacking, and most data are extrapolated from studies on olive oil or polyphenol-rich diets. Therefore, while there is a scientific basis for tyrosol’s potential benefit, the evidence is not yet robust or specific enough to strongly recommend it as a stand-alone treatment for metabolic syndrome.

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