Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Thylakoids are membrane-bound compartments inside chloroplasts, involved in the photosynthetic process in plants. In recent years, isolated thylakoids from spinach and other green plants have been studied for their potential metabolic health benefits, particularly in relation to metabolic syndrome. The scientific interest is based on thylakoids’ ability to delay fat digestion and absorption, increase satiety, and modulate appetite-regulating hormones such as cholecystokinin (CCK) and ghrelin. Several randomized controlled trials (RCTs) and animal studies have demonstrated that supplementation with thylakoid-rich extracts can contribute to reduced hunger, decreased body weight, improved glucose homeostasis, and favorable changes in blood lipid profiles in overweight or obese individuals. For example, studies published in journals like Appetite (2013) and Journal of Functional Foods (2015) have shown that daily thylakoid supplementation can reduce body weight and waist circumference and improve markers of metabolic health over periods ranging from a few weeks to several months. However, while these results are promising, most studies are of short duration and use relatively small sample sizes. There is a need for larger and longer-term trials to confirm these effects and to establish optimal dosing. Nonetheless, current scientific evidence supports a moderate level of validation for thylakoid use as a dietary adjunct in the management of metabolic syndrome.

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