Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Glucosinolates are naturally occurring compounds found predominantly in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage. There is emerging scientific interest in their role in metabolic health, including potential effects on Metabolic Syndrome (MetS). Laboratory studies and some small clinical trials have investigated the influence of glucosinolate-derived metabolites, such as sulforaphane, on pathways relevant to MetS, including inflammation, oxidative stress, and insulin sensitivity. Some animal and in vitro studies suggest that these compounds may modulate glucose metabolism, reduce adipogenesis, and improve lipid profiles.

However, human evidence remains limited and inconsistent. A few small-scale clinical trials have reported modest improvements in markers like fasting blood glucose and lipid levels with broccoli sprout or extract supplementation, but these results are not uniform and often involve small sample sizes and short durations. Major guidelines do not currently recommend glucosinolates or their derivatives specifically for Metabolic Syndrome management.

In summary, while there is a scientific rationale and preliminary evidence suggesting potential benefits of glucosinolates for Metabolic Syndrome, the current human data are insufficient to draw strong conclusions. More high-quality, large-scale clinical trials are needed to confirm efficacy and determine appropriate dosing and safety profiles.

More about Glucosinolates (unspecified)
More about Metabolic Syndrome

Other ingredients used for Metabolic Syndrome

Other health conditions supported by Glucosinolates (unspecified)

Products containing Glucosinolates (unspecified)