Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flax lignans, particularly secoisolariciresinol diglucoside (SDG), have been the subject of scientific research regarding their potential benefits in metabolic syndrome. Metabolic syndrome is a cluster of conditions—including increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels—that increase the risk of heart disease, stroke, and diabetes. Several animal and human studies suggest that flax lignans may have beneficial effects due to their antioxidant, anti-inflammatory, and lipid-lowering properties.

Randomized controlled trials and meta-analyses have shown that flaxseed supplementation (which is rich in lignans) can modestly improve some metabolic syndrome parameters, particularly by lowering blood pressure and improving lipid profiles. For example, a 2016 meta-analysis in "Clinical Nutrition" found that flaxseed supplementation led to significant reductions in both systolic and diastolic blood pressure. Some studies also show improvements in markers of glycemic control and inflammation, although results are mixed and often depend on the population studied and the form/dose of flax used.

While the evidence is promising, it is not yet conclusive, and most studies use whole flaxseed or flaxseed powder rather than isolated lignans. Nevertheless, lignans are believed to be one of the major active components. Overall, the use of flax lignans for metabolic syndrome is supported by moderate-quality scientific evidence, but more research is needed to define optimal dosing and specific effects.

More about Flax lignans
More about Metabolic Syndrome

Other ingredients used for Metabolic Syndrome

Other health conditions supported by Flax lignans

Products containing Flax lignans