Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitex, also known as Vitex agnus-castus or chaste tree, has a long history of use in traditional medicine to address menstrual irregularities, particularly in Europe and the Mediterranean. Its use is rooted in the belief that it helps balance female hormones. Scientifically, several randomized controlled trials and systematic reviews have investigated the efficacy of Vitex for menstrual irregularities, including premenstrual syndrome (PMS), luteal phase defects, and irregular menstrual cycles. The proposed mechanism involves modulation of pituitary hormones, particularly prolactin, which can influence the menstrual cycle.

A 2017 systematic review in Phytomedicine noted that Vitex agnus-castus extracts demonstrated greater efficacy than placebo in normalizing menstrual cycles and alleviating symptoms of PMS in several studies. Some clinical trials report improvements in cycle regularity among women with oligomenorrhea or cycle disturbances, though study quality varies and sample sizes are often limited. The German Commission E has approved Vitex for menstrual irregularities, lending further support to its use in Europe.

Despite the promising findings, methodological weaknesses and heterogeneity in dosing and outcome measures mean that the overall strength of the evidence is moderate. More rigorous, large-scale studies are needed to confirm its efficacy and safety. In summary, Vitex is used to support menstrual irregularity based on both traditional use and a moderate body of scientific evidence.

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