Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phytoestrogens are plant-derived compounds with estrogen-like activity, most notably found in soy, flaxseed, and some other foods. Their use to support or treat menstrual irregularity is primarily based on the fact that phytoestrogens can bind to estrogen receptors and exert weak estrogenic or anti-estrogenic effects. Scientific studies have investigated their effects on menstrual cycles, particularly in populations experiencing menstrual irregularities, such as perimenopausal women or those with polycystic ovary syndrome (PCOS). Some evidence suggests that phytoestrogens can influence menstrual cycle length and hormonal balance: for example, soy isoflavones have been shown in a few small studies to slightly lengthen the follicular phase or modulate hormone levels. However, the quality and quantity of scientific evidence supporting their use for general menstrual irregularity is limited. Most clinical trials are small, have short durations, or focus primarily on menopausal symptoms rather than menstrual cycle regulation in premenopausal women. Meta-analyses and systematic reviews often conclude that evidence is inconclusive or low-quality, with no clear consensus on efficacy. Overall, while there is a scientific rationale and some preliminary evidence for the use of phytoestrogens in menstrual irregularity, the support is modest and insufficient for strong clinical recommendations. More robust, large-scale studies are needed to confirm efficacy and determine optimal dosing and indications.

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