Evidence supporting the use of: Calotropis gigantea
For the health condition: Menstrual Irregularity

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Calotropis gigantea, commonly known as crown flower or "arka" in Ayurveda, has a long-standing history of use in traditional medicine systems such as Ayurveda and Unani. In these traditions, various parts of the plant (particularly the root bark and latex) have been used for a range of gynecological disorders, including menstrual irregularities, amenorrhea (absence of menstruation), and dysmenorrhea (painful menstruation). Classical Ayurvedic texts mention Calotropis gigantea as an emmenagogue, meaning it is believed to stimulate or regulate menstrual flow. Preparations made from the root or latex are sometimes used in formulations intended to restore menstrual regularity or address hormonal imbalances. However, the scientific evidence supporting these uses is limited. While some in vitro and animal studies have explored the plant’s phytochemical profile—identifying compounds with possible estrogenic or uterine stimulant properties—there is a lack of robust clinical trials in humans substantiating its efficacy or safety for menstrual irregularity. Additionally, the plant contains potent bioactive compounds (such as cardiac glycosides and alkaloids) that can be toxic if not used properly. Therefore, its use for menstrual irregularities remains primarily rooted in traditional practices, with limited scientific validation. Caution is advised, and consultation with a healthcare provider is recommended before use.

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