Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Abuta (Cissampelos pareira), commonly known as "Velvetleaf" or "Pareira," has a long-standing history in traditional medicine systems such as Ayurveda and South American herbal practices. It has been used for various gynecological issues, including menstrual irregularities, dysmenorrhea, and as an emmenagogue (to promote menstrual flow). The traditional use is primarily based on empirical observations and the plant's reputed effects on the female reproductive system. In Ayurveda, Abuta is considered a uterine tonic and is often prescribed in formulations aimed at regulating the menstrual cycle and alleviating menstrual discomfort.

However, while there are some preclinical studies on Cissampelos pareira indicating potential anti-inflammatory, antispasmodic, and hormonal modulation properties, robust clinical trials in humans specifically addressing its efficacy for menstrual irregularity are lacking. Most available scientific literature focuses on its ethnobotanical uses and preliminary pharmacological activities, not on well-controlled studies for menstrual regulation. Therefore, while there is a foundation in traditional medicine for its use, scientific validation remains limited.

In summary, Abuta's use for menstrual irregularity is justified primarily by traditional knowledge rather than strong scientific evidence. The strength of evidence supporting its use for this condition is modest, largely owing to its longstanding place in herbal medicine rather than modern clinical validation.

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