Evidence supporting the use of: Vitamin E (tocopheryl acetate)
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Vitamin E (tocopheryl acetate) has been used traditionally for the management of menopausal symptoms, particularly hot flashes. Some early clinical observations and anecdotal reports suggested that Vitamin E might offer mild relief from vasomotor symptoms, and it became popular in the mid-20th century as a non-hormonal remedy for menopause. However, scientific validation for its effectiveness is limited. Most clinical trials conducted have been small, with mixed or inconclusive results. A few studies have shown a minor reduction in the frequency or severity of hot flashes compared to placebo, but the effect size is generally modest and not consistently replicated. Systematic reviews and guidelines from major medical organizations do not recommend Vitamin E as a primary or effective treatment for menopause-related symptoms due to insufficient evidence. Overall, the use of Vitamin E for menopause is based more on its historical and traditional use rather than robust scientific data.

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