Evidence supporting the use of: Vitamin E (alpha-tocopherol)
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitamin E (alpha-tocopherol) has been used traditionally to help manage menopausal symptoms, particularly hot flashes and vaginal dryness. The rationale stems from early reports and anecdotal experiences suggesting that Vitamin E's antioxidant properties might mitigate vasomotor symptoms associated with menopause. Some small clinical studies, mainly from the mid-to-late 20th century, hinted at modest benefits—such as a reduction in the frequency or severity of hot flashes when compared to placebo. For example, a 2007 double-blind randomized controlled trial published in "Gynecologic and Obstetric Investigation" found a slight decrease in hot flash frequency with Vitamin E supplementation, but the effect was minimal and not as robust as with hormone therapy or other pharmacological interventions.

However, more recent reviews and meta-analyses generally conclude that the evidence is weak and inconsistent. Major professional organizations do not recommend Vitamin E as a first-line or evidence-based treatment for menopausal symptoms. Despite this, Vitamin E is still sometimes found in over-the-counter menopausal support supplements, reflecting its traditional rather than scientifically validated role. Overall, the use of Vitamin E for menopause is supported more by tradition and historical use than by strong scientific evidence.

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Products containing Vitamin E (alpha-tocopherol)

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