Evidence supporting the use of: Rehmannia glutinosa
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rehmannia glutinosa, known as “Dihuang” in Traditional Chinese Medicine (TCM), has a long history of use for supporting women’s health, particularly during menopause. In TCM, rehmannia is often included in formulas such as Liu Wei Di Huang Wan and Zhi Bai Di Huang Wan, which are prescribed to address symptoms believed to result from “Kidney Yin deficiency”—a pattern associated with menopause symptoms like hot flashes, night sweats, and irritability. Historical texts and modern TCM practitioners cite rehmannia’s ability to “nourish Yin and replenish essence,” aiming to restore balance during the menopausal transition.

However, scientific evidence supporting the efficacy of rehmannia for menopause is limited. Some animal studies suggest possible estrogenic effects or influence on hormone regulation, but robust human clinical trials are lacking. A handful of small studies and reviews indicate potential benefits when used in multi-herb formulas, but it is difficult to isolate the effect of rehmannia itself. Thus, its use for menopause is primarily justified by tradition rather than rigorous scientific validation. Women considering rehmannia for menopause-related symptoms should consult a qualified healthcare provider, as herb-drug interactions and contraindications may exist.

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