Evidence supporting the use of: Pollen (unspecified)
For the health condition: Menopause

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Pollen extracts, particularly those derived from Swedish flower pollen (often from rye, timothy, and maize), have been studied for their potential to alleviate menopausal symptoms such as hot flashes, irritability, and sleep disturbances. The scientific evidence supporting the use of pollen extracts for menopause is limited but does exist. Several small-scale randomized controlled trials and observational studies, primarily from Europe, have reported that certain standardized pollen extracts (e.g., branded as "Cernilton" or "Femal") may reduce the frequency and severity of hot flashes and improve quality of life in menopausal women. The proposed mechanisms include phytoestrogenic effects, serotonergic modulation, and antioxidant properties; however, the pollen extracts typically used are processed to remove allergenic proteins and are not the same as unprocessed bee pollen.

Despite these findings, the overall quality and quantity of evidence are moderate to low. Meta-analyses and systematic reviews note methodological limitations, small sample sizes, and short durations in most studies. Nevertheless, pollen extract is sometimes recommended as a non-hormonal option for menopausal symptom relief, especially where hormone therapy is contraindicated or undesired. In summary, there is some scientific validation for the use of specific, standardized pollen extracts in menopause, but the evidence is not robust, and further large-scale, high-quality trials are needed to confirm efficacy and safety.

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