Evidence supporting the use of: Omega-3 fatty acids
For the health condition: Menopause
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Omega-3 fatty acids, primarily found in fish oil (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]), have some scientific basis for use in supporting menopausal health, particularly regarding mood and cardiovascular symptoms. Some studies indicate that omega-3 supplementation may help reduce the severity of depressive symptoms and improve mood in peri- and post-menopausal women, possibly by modulating neurotransmitter function and reducing inflammation. Additionally, as menopause increases cardiovascular risk due to declining estrogen, omega-3s are recognized for their positive effects on lipid profiles and cardiovascular health, making them a logical adjunct in menopausal care for heart protection.
However, evidence supporting omega-3s for classic vasomotor symptoms of menopause—such as hot flashes and night sweats—is weak. Several randomized controlled trials and meta-analyses have failed to show consistent or clinically significant reductions in hot flash frequency or severity with omega-3 supplementation. Clinical guidelines do not currently recommend omega-3s specifically for menopausal symptom relief, though they may be considered for mood or cardiovascular benefits.
In summary, while omega-3 fatty acids have a strong scientific rationale for general health and some evidence for mood support in menopause, their effectiveness for core menopausal symptoms is limited. The overall evidence supporting their use for menopause is modest (rated 2/5), based on weak but present clinical trial data for certain symptoms, and stronger evidence for associated health risks like depression and cardiovascular disease.
Other ingredients used for Menopause
7-hydroxymatairesinol (HMR)alfalfa
aloe vera
ashwagandha
asparagus
astragalus
black cohosh
black currant
Indian frankincense
bupleurum falcatum
burdock
calcium
chaste tree
cordyceps
damiana
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dog rose
dong quai root
eleuthero
evening primrose oil
fenugreek
fish oil
flaxseed
genistein
genistin
hibiscus
HMR lignan
hops
knotweed
jujube
kudzu
licorice root
lignans
maca
marine lipid
melatonin
moringa
motherwort
nettle
okra
omega-3 fatty acids
ophiopogon root
pollen
pomegranate
rehmannia glutinosa
reishi mushroom
rose oil
saffron
sage
soybean
valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
seaweed
wild yam
red clover
atractylodes
smilax
rubia cordifolia
bee pollen
lingzhi
root tuber
dioscorea
royal jelly
Equol (proprietary)
anemarrhena asphodeloides
barrenwort
goji berry
amaranth
soy isoflavones
27-deoxyactein
8-Prenylnaringenin
akebia
Antler
Achyranthes
Alchemilla
Agrimonia pilosa
Agnuside
Ashoka
Anemarrhena
Atractylone
Black Seed
Banyan
Bioflavonoids
Black root
Chinese Silkvine
Cohosh
Clary sage
Cnidium
Cynomorium
Crinum latifolium
DHEA
Danshen
Daidzein
Durian
Dong Quai
Elk antler
Evening Primrose
Estrogen
Isoflavones
Lotus
Prickly Pear Cactus
Rose
Rhubarb
Soy Protein
Vervain
Other health conditions supported by omega-3 fatty acids
AcneAcquired Immune Deficiency Syndrome
Addictions (drugs)
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Aging (prevention)
Alcoholism
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
Anger (excessive)
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Autoimmune Disorders
Backache
Bipolar Mood Disorder
Birth Defects (prevention)
Blood Clots (prevention of)
Bloodshot Eyes
Body Building
Broken Bones
Bulimia
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Cardiovascular Disease
Cartilage Damage
Cholesterol (high)
Cholesterol (low)
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Circulation (to the brain)
Concentration (poor)
Concussions
Confusion
Congestive Heart Failure
Dementia
Depression
Diabetes
Dysmenorrhea
Eczema
Emotional Sensitivity
Endometriosis
Epilepsy
Exercise
Eye Problems
Eyes (red or itching)
Eyesight (poor)
Fat Metabolism (poor)
Fatigue
Fatty Liver Disease
Fibrosis
Free Radical Damage
Glaucoma
Gout
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Hearing Loss
Heart (weakness)
Heart Fibrillation or Palpitations
Hepatitis
Hypertension
Infertility
Inflammation
Inflammatory Bowel Disorders
Irritability
Lou Gehrig's Disease
Lupus
Macular Degeneration
Memory and Brain Function
Menopause
Metabolic Syndrome
Migraine
Muscular Dystrophy
Nerve Damage
Neuralgia and Neuritis
Numbness
Osteoporosis
Parkinson's Disease
Peripheral Neuropathy
Pets (supplements for)
PMS Type D
PMS Type P
PMS Type S
Polyps
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Psoriasis
Raynaud's Disease
Rheumatoid Arthritis
Rosacea
Schizophrenia
Seasonal Affective Disorder
Seborrhea
Seizures
Senility
Sickle Cell Anemia
Skin (dry and/or flaky)
Skin Care (general)
Spinal Disks
Strokes
Surgery (healing from)
Surgery (preparation for)
Thinking (cloudy)
Thrombosis
Triglycerides (high)
Triglycerides (low)
Vaginal Dryness