Evidence supporting the use of: Motherwort
For the health condition: Menopause
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Motherwort (Leonurus cardiaca) has a long history of use in traditional herbal medicine, particularly in European and Chinese practices. Historically, it has been used to support women’s reproductive health, including during menopause. The herb is believed to have mild sedative, antispasmodic, and cardiotonic properties, which traditional herbalists claim can help with common menopausal symptoms such as anxiety, palpitations, and mild mood disturbances.
The rationale for using motherwort in menopause is largely based on its calming effects and its reputation for “easing the heart” both emotionally and physically. In folk medicine, it was often recommended for women experiencing irritability, insomnia, or heart palpitations around menopause. Some herbal texts also note its use for supporting menstrual regularity and easing uterine discomfort, which can overlap with perimenopausal symptoms.
From a scientific perspective, there is limited clinical research specifically evaluating motherwort for menopause. Most evidence is anecdotal or comes from broader studies on its effects on anxiety or cardiovascular health. While some preclinical studies suggest mild sedative and antispasmodic effects, high-quality human trials are lacking. As such, its use for menopause is supported primarily by tradition, with modest evidence from historical use but little robust scientific validation.
Other ingredients used for Menopause
7-hydroxymatairesinol (HMR)alfalfa
aloe vera
ashwagandha
asparagus
astragalus
black cohosh
black currant
Indian frankincense
bupleurum falcatum
burdock
calcium
chaste tree
cordyceps
damiana
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dog rose
dong quai root
eleuthero
evening primrose oil
fenugreek
fish oil
flaxseed
genistein
genistin
hibiscus
HMR lignan
hops
knotweed
jujube
kudzu
licorice root
lignans
maca
marine lipid
melatonin
moringa
motherwort
nettle
okra
omega-3 fatty acids
ophiopogon root
pollen
pomegranate
rehmannia glutinosa
reishi mushroom
rose oil
saffron
sage
soybean
valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
seaweed
wild yam
red clover
atractylodes
smilax
rubia cordifolia
bee pollen
lingzhi
root tuber
dioscorea
royal jelly
Equol (proprietary)
anemarrhena asphodeloides
barrenwort
goji berry
amaranth
soy isoflavones
27-deoxyactein
8-Prenylnaringenin
akebia
Antler
Achyranthes
Alchemilla
Agrimonia pilosa
Agnuside
Ashoka
Anemarrhena
Atractylone
Black Seed
Banyan
Bioflavonoids
Black root
Chinese Silkvine
Cohosh
Clary sage
Cnidium
Cynomorium
Crinum latifolium
DHEA
Danshen
Daidzein
Durian
Dong Quai
Elk antler
Evening Primrose
Estrogen
Isoflavones
Lotus
Prickly Pear Cactus
Rose
Rhubarb
Soy Protein
Vervain
Other health conditions supported by motherwort
AmenorrheaAnxiety
Anxiety Disorders
Arrhythmia
Cardiovascular Disease
Cramps (menstrual)
Dysmenorrhea
Heart (weakness)
Heart Fibrillation or Palpitations
Hypertension
Insomnia
Menopause
Menstrual Irregularity
Menstruation (scant)
Nervous Exhaustion
Nervousness
PMS (general)
PMS Type A
Stress
Worry