Marine lipids, particularly those rich in omega-3 fatty acids such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), have been investigated for their potential to support menopausal health. The rationale is primarily based on their anti-inflammatory properties and possible benefits for cardiovascular health, mood regulation, and vasomotor symptoms (such as hot flashes). Several randomized controlled trials and meta-analyses have explored the effect of omega-3 supplementation on menopausal symptoms. While some studies report modest improvements, especially in mood and depressive symptoms, the evidence for relief of classic menopausal symptoms like hot flashes and night sweats is inconsistent and generally weak. For example, a 2018 meta-analysis published in "Climacteric" found limited and inconsistent benefits of omega-3 supplementation for vasomotor symptoms. However, there is stronger support for the cardiovascular and mood benefits of marine lipids during menopause, as this period is associated with increased risk for cardiovascular disease and mood disorders. Overall, while the use of marine lipids for menopause is grounded in scientific investigation and some biological plausibility, the strength of evidence for symptom relief is low, justifying a moderate evidence rating.