Evidence supporting the use of: Lignan (unspecified)
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Lignans are a group of polyphenolic compounds found in plants, particularly seeds such as flaxseed, as well as whole grains and some vegetables. Traditionally, lignan-rich foods, especially flaxseed, have been used for the management of menopausal symptoms. The rationale is that lignans are phytoestrogens—plant-derived compounds with weak estrogenic activity—which may help compensate for declining estrogen levels during menopause and thus alleviate symptoms such as hot flashes and night sweats. Scientific evidence is limited and inconsistent. Some small clinical studies have shown modest reductions in menopausal symptoms like hot flashes when women consumed flaxseed or lignan supplements, but other trials have found no significant benefit compared to placebo. Systematic reviews and meta-analyses generally conclude that the evidence is not strong enough to recommend lignans as a primary treatment for menopausal symptoms, though they are considered safe as part of a balanced diet. In summary, the use of lignans for menopause is primarily justified by traditional use rather than robust scientific validation, and the strength of the evidence is rated as low to moderate (2 out of 5).

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Products containing Lignan (unspecified)

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