Evidence supporting the use of: Isoflavones
For the health condition: Menopause

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Isoflavones are plant-derived compounds found primarily in soybeans and other legumes. They possess a chemical structure similar to estrogen, allowing them to weakly bind to estrogen receptors in the body. This has led to their use as a potential treatment for menopausal symptoms, which are partly caused by declining estrogen levels. Several clinical studies and meta-analyses have examined the efficacy of isoflavones for menopause-related symptoms, particularly hot flashes (vasomotor symptoms). Results are mixed: some randomized controlled trials and systematic reviews suggest a modest reduction in the frequency and severity of hot flashes compared to placebo, while others find minimal or no effect.

For example, a 2021 Cochrane review concluded that isoflavones may offer a small benefit in reducing hot flushes and night sweats, but the effect is likely less than that of hormone replacement therapy (HRT). Safety profiles appear favorable, with few adverse effects reported in short-term studies. However, long-term safety data and effects on other menopausal symptoms (such as vaginal dryness or mood changes) are less robust. Overall, the use of isoflavones for menopause is supported by moderate scientific evidence, but they are generally considered less effective than conventional HRT. Their popularity is partly due to their "natural" origin and better safety profile for women who cannot or choose not to take HRT.

More about Isoflavones
More about Menopause

Products containing Isoflavones

We currently have no products on Caring Sunshine that contain this ingredient.