Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Honduran Sarsaparilla (Smilax regelii or related Smilax species) has been used traditionally in various folk medicine systems, especially in Central and South America, for a variety of ailments including hormonal imbalances and symptoms associated with menopause. Historical records and herbal texts mention its use as a general tonic and blood purifier, and it has sometimes been recommended for women experiencing symptoms such as hot flashes, night sweats, or mood swings attributed to menopause. The rationale for its use is largely based on its perceived ability to support hormonal balance and its content of plant sterols, which were once hypothesized to have mild estrogenic effects. However, these traditional uses are not strongly supported by rigorous clinical trials or scientific research. Existing scientific literature offers little to no evidence specifically validating sarsaparilla for menopause symptom relief. Most contemporary herbal medicine references mention sarsaparilla’s traditional uses, but acknowledge the lack of direct clinical evidence. Therefore, while its use is rooted in tradition, the supporting evidence is weak, earning it a low evidence rating.

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