Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Estrogen is scientifically validated as a primary treatment for menopausal symptoms. Menopause is characterized by a natural decline in estrogen production, leading to symptoms such as hot flashes, night sweats, vaginal dryness, mood changes, and increased risk of osteoporosis. Numerous randomized controlled trials and systematic reviews have demonstrated that estrogen therapy (either alone or in combination with progestin for women with a uterus) is effective in alleviating vasomotor symptoms (like hot flashes) and urogenital atrophy. The Women's Health Initiative and other large-scale studies have provided robust data on both the benefits and risks associated with estrogen therapy. Clinical guidelines from organizations such as the North American Menopause Society, Endocrine Society, and American College of Obstetricians and Gynecologists endorse the use of estrogen for moderate to severe menopausal symptoms when not contraindicated. Estrogen has also been shown to help maintain bone mineral density and reduce fracture risk, though it is not the first-line therapy solely for osteoporosis prevention. Risks associated with estrogen therapy include increased risk of thromboembolism, stroke, and in some contexts, breast cancer, so therapy should be individualized. Overall, the use of estrogen for menopause is firmly rooted in scientific evidence, with decades of clinical research supporting its efficacy and guiding its appropriate use.

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Other ingredients used for Menopause

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