Chinese Chastetree (Vitex negundo) is primarily used in Traditional Chinese Medicine (TCM) and Ayurveda, rather than Western herbalism, to support women’s health, including menstrual regulation and relief of menopausal symptoms. Historically, this plant has been employed to alleviate symptoms such as hot flashes, mood swings, and insomnia associated with menopause. Its use is recorded in classical TCM texts, where it is often prescribed in formulations meant to dispel wind and heat, which are concepts linked to menopausal symptoms in TCM theory.

However, while the related species Vitex agnus-castus (Chaste Tree or Monk’s Pepper) has been more extensively studied and used in Western herbal medicine for reproductive hormone regulation, the scientific evidence specific to Vitex negundo (Chinese Chastetree) is limited. A few animal and in vitro studies suggest anti-inflammatory and possible estrogenic effects, but robust clinical trials in humans for menopausal symptoms are lacking. Thus, any support for its use in menopause is grounded in historical and traditional practice rather than modern clinical validation.

In summary, Chinese Chastetree is used traditionally for menopause support, but its efficacy is not well-established in scientific literature. The evidence level is low, reflecting the need for more rigorous research into its effects and mechanisms for this specific health condition.