Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bifidobacterium (mixed strains) is being investigated for its potential to support menopausal symptoms, but the scientific evidence remains limited and preliminary. Some studies suggest that changes in the gut microbiome occur during menopause, potentially affecting estrogen metabolism, inflammation, and overall health. Bifidobacterium species are known to have beneficial effects on gut health, immune modulation, and inflammation in general. However, only a few small-scale clinical trials and animal studies have specifically examined the impact of Bifidobacterium supplementation on menopausal symptoms such as hot flashes, mood changes, or bone health. These studies sometimes report modest improvements in quality of life or metabolic parameters but are often limited by small sample sizes, short duration, and mixed results.

There is currently no strong consensus or guideline recommending Bifidobacterium specifically as a treatment for menopause. Its use is more often rationalized by its broad benefits to gut and immune health, which might indirectly support women during menopause, rather than by direct evidence of efficacy for typical menopausal symptoms. More robust, large-scale human clinical trials are needed to clarify its role and efficacy. Therefore, the scientific basis for using Bifidobacterium to treat or support menopause is limited but emerging, justifying a low-to-moderate evidence rating.

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