Evidence supporting the use of: Pentacyclic Oxindole Alkaloids
For the health condition: Memory and Brain Function

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Pentacyclic oxindole alkaloids are primarily found in the plant Uncaria tomentosa, commonly known as Cat's Claw. The traditional use of Cat's Claw in indigenous Amazonian medicine is well-documented, where it has been used for a variety of health conditions, mainly related to inflammation, immune support, and general wellness. However, there is little historical evidence suggesting that Cat's Claw or its pentacyclic oxindole alkaloids were traditionally used specifically to support memory or brain function. In modern times, some dietary supplements include Cat's Claw extracts for cognitive support, but this is largely extrapolated from its anti-inflammatory properties and not from robust traditional or scientific evidence.

Scientific studies investigating the direct effects of pentacyclic oxindole alkaloids on memory or cognition are limited and largely preliminary. Most available research focuses on their immunomodulatory and anti-inflammatory actions, rather than neuroprotective or cognitive effects. A few in vitro and animal studies have hinted at potential neuroprotective benefits, but there is currently insufficient clinical evidence to support their use for memory or brain function in humans. Therefore, while there is some traditional use of Cat's Claw, its application specifically for memory and brain function is weakly supported and lacks both strong traditional justification and scientific validation.

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Products containing Pentacyclic Oxindole Alkaloids

We currently have no products on Caring Sunshine that contain this ingredient.