Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Omega-3 fatty acids, particularly EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), have been widely studied for their effects on memory and brain function. These essential fatty acids are important structural components of neuronal cell membranes and play a role in modulating neurotransmission, inflammation, and neuroprotection. Epidemiological studies have shown that populations with high consumption of omega-3-rich fish tend to have lower rates of cognitive decline and dementia.

Several randomized controlled trials (RCTs) have investigated omega-3 supplementation in both healthy individuals and those with mild cognitive impairment (MCI) or dementia. Results are mixed: some studies have reported modest improvements in memory, attention, and executive function, especially in older adults with low baseline omega-3 levels or mild cognitive deficits. However, other large RCTs have failed to demonstrate significant benefits in cognitive outcomes, particularly in healthy adults or those with established dementia.

A 2020 Cochrane review concluded that while omega-3 supplementation did not prevent cognitive decline in healthy older adults, there may be small benefits for those with mild cognitive impairment. Mechanistically, DHA is highly concentrated in brain tissue and supports synaptic plasticity and neuronal survival, which could underlie cognitive benefits. Overall, omega-3 fatty acids are scientifically validated for supporting brain health, but the evidence for substantial improvements in memory and function is moderate, with the greatest potential benefit seen in populations at risk for cognitive decline.

More about omega-3 fatty acids
More about Memory and Brain Function

Other ingredients used for Memory and Brain Function

Other health conditions supported by omega-3 fatty acids

Products containing omega-3 fatty acids

Nature's Sunshine Flax Seed Oil (With Lignans)