Evidence supporting the use of: Medium Chain Triglycerides
For the health condition: Memory and Brain Function
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Medium Chain Triglycerides (MCTs) have gained attention for their potential benefits on memory and brain function, especially in the context of aging and neurodegenerative diseases such as Alzheimer's disease. The scientific rationale centers on the fact that MCTs are rapidly metabolized in the liver to produce ketone bodies, which can serve as an alternative energy source for the brain, particularly when glucose metabolism is impaired. Some clinical studies, such as those using MCT-rich medical foods, have shown modest cognitive improvements in individuals with mild to moderate Alzheimer's disease, particularly in those without the APOE4 genotype. However, these effects are generally small, and not all studies have shown benefit. Evidence in healthy individuals or those with mild cognitive impairment is limited and inconsistent.
Systematic reviews and meta-analyses conclude that while there is a biological plausibility and some early positive findings, the overall evidence for MCTs in supporting memory and brain function is preliminary and not robust. The use of MCTs for brain health is not rooted in traditional medicine but in recent scientific exploration. Larger, longer-term studies are needed to confirm efficacy, optimal dosing, and target populations. Thus, while there is a scientific basis and some supportive data, the strength of the evidence is currently rated as low to moderate.
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Other ingredients used for Memory and Brain Function
2'-Fucosyllactoseacai berry
acetyl l-carnitine
algal oil
alpha-pinene
amino acids
anchovies
anthocyanins
ashwagandha
asparagus
astaxanthin
waterhyssop
beet
berry flavor
beta caryophyllene
bifidobacterium longum
bilberry
black currant
black garlic
sesame
black tea
blackberry
blueberry
Indian frankincense
broccoli
caprylic acid
catechins
caterpillar mushroom
chaga mushroom
Chinese salvia root
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
cordyceps
creatine monohydrate
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish protein
folate
fruit and vegetable blend (proprietary)
fruit blend (proprietary)
ginkgo biloba
glycerophosphocholine (GPC)
gooseberry
gotu kola
grape
green tea
guarana
guayusa
hesperetin
huperzine A
inositol
jujube
kale
krill oil
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-carnitine
l-carnosine
l-serine
l-taurine
l-theanine
l-tyrosine
lactobacillus reuteri
lecithin
lion's mane
lutein
luteolin
maca
mackerel
marine lipid
matcha
medium chain triglycerides (MCT)
moringa
muira puama
Acetyl-L-Tyrosine
naringin
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oat
oleic acid
olive
omega-3 fatty acids
ophiopogon root
perilla
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
pine bark
pollen
polygala root
pomegranate
pregnenolone
prolyl endopeptidase (PEP)
pumpkin
pyrroloquinoline disodium salt
quail egg
quercetin
reishi mushroom
resveratrol
rhodiola
rutin
saffron
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
black ginger
specialized pro-resolving mediators (SPMs)
spinach
spirulina
strawberry
sulforaphane glucosinolate
threonic acid
tocotrienols
tomato
trans-pterostilbene
almond fruit
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
velvet bean
vinpocetine
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
suma
jiaogulan
tinospora cordifolia
lingzhi
morus
root tuber
ferulic acid
chrysanthemum
cistanche
lotus seed
royal jelly
terpene lactones
purslane
yerba mate
biota seed
goji berry
algae
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
1,3,7-Trimethylpurine-2,6-dione
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
5-methyltetrahydrofolate glucosamine
7,8-Dihydroxyflavone
Arachidonic Acid
Apigenin
Aronia melanocarpa
Anserine
Alpha glyceryl
Andrographolide
Avocado
Agmatine
Adrafinil
Acetylcholine
Amentoflavone
Agarwood
Acacetin
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Acer Truncatum bunge
Aniracetam
anthocyanosides
Black Seed
Bilobalide
Butylphthalide
Beta-hydroxybutyrate
Breadnut
Blepharis
Beef liver
Baccosides
Bacopin
Baicalein
Basidiomycota
Boswellia
Brahmi
Bacopa
Blue-Green Alage
Bifidobacteria
bacoside
Baicalin
Bird's nest
Centrophenoxine
Camellia sinensis
Centella triterpenes
Chinese Mountain Ant
Cyanobacteria
Carnosine
Catalpol
Chebulic acid
Cod Liver Oil
Codonopsis
Cyanidin
Cruciferous
Centella asiatica
Cinnamic Acid
Chocolate
Chinese Ligustrum berry
Creatine
Catuaba
Convolvulus prostratus
Crocetin
Convolvulus Pluricaulis
Celastrus
Cytidine
cola nut
Canscora
Currant
Carnosic acid
Docosahexaenoic Acid
Danshen
Dendrobium
Decursin
Decursinol
Dibenzo-alpha pyrones
Date
epicatechin
Egg
Ergothioneine
Elk antler
Emblicanin
Eicosapentaenoic Acid
Eucommia ulmoides
Enokitake
Folic Acid
Fucosterol
Fo-Ti
Fish
Flavanones
Flavoglycosides
Flavans
Frankincense
Flavanols
Flammulina velutipes
Flavones
Gallic Acid
Ginsenosides
Garcinol
Ginkgetin
Galantamine
glucose
Glutamate
Ginkgolides
Glycosphingolipids
Galangin
Ginkgo Flavone Glycoside
Ginkgoside
Guaranine
Glycine
Ginkgoheteroside
Glucoraphanin
Gastrodin
Periwinkle
Shellfish
walnut
yohimbine
Other health conditions supported by Medium Chain Triglycerides
Alzheimer's DiseaseCancer (natural therapy for)
Cancer Treatment (reducing side effects)
Dementia
Diabetes
Digestion (poor)
Epilepsy
Fat Metabolism (poor)
Fatty Liver Disease
Inflammation
Inflammatory Bowel Disorders
Memory and Brain Function
Multiple Sclerosis
Parkinson's Disease
Wasting
Weight Loss