Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Jatamansi (Nardostachys jatamansi) has a long history of use in traditional Ayurvedic and Unani medicine for supporting memory and brain function. Historically, it has been described as a “medhya,” or brain tonic, believed to enhance cognitive abilities, promote mental clarity, and reduce stress. Traditional practitioners have used Jatamansi for conditions involving memory loss, insomnia, and anxiety, attributing its effects to its calming and neuroprotective properties.

Some preclinical studies in animals provide preliminary scientific support for these traditional uses. For example, research has shown that Jatamansi extracts may exhibit antioxidant effects, reduce neuroinflammation, and improve learning and memory in animal models of cognitive impairment. Key compounds, such as jatamansone (spirojatamol), are thought to mediate these effects by modulating neurotransmitter systems and protecting neuronal cells from oxidative stress. However, high-quality clinical evidence in humans is sparse, with few rigorous trials conducted to confirm efficacy or establish optimal dosing.

Overall, while traditional use is well-established and there is some supportive experimental evidence, definitive scientific validation through human clinical trials remains limited. Therefore, the use of Jatamansi for memory and brain function is justified primarily by tradition, with a moderate level of supporting evidence.

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