Evidence supporting the use of: Ginkgoheteroside
For the health condition: Memory and Brain Function
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Ginkgoheteroside is a term used to refer to the flavonol glycosides present in Ginkgo biloba extracts, which are among the key active constituents of standardized Ginkgo preparations. The use of Ginkgo biloba extract for supporting memory and brain function is backed by both traditional use (notably in Chinese medicine) and a substantial body of modern scientific research. However, the evidence for the specific role of ginkgoheterosides (as opposed to other components like terpene lactones) is less clear, as most studies evaluate the effects of the whole extract rather than isolated ginkgoheterosides.
Systematic reviews and meta-analyses of randomized controlled trials (RCTs) suggest that standardized Ginkgo biloba extracts (which contain ginkgoheterosides) may confer modest benefits in cognitive function, particularly in patients with dementia or mild cognitive impairment. Some studies have reported improvements in memory, attention, and executive function, although results are mixed and effect sizes are generally small. Proposed mechanisms include antioxidant effects, enhancement of cerebral blood flow, and neuroprotective actions, which are attributed in part to the flavonol glycosides.
Overall, the scientific evidence for Ginkgo biloba extract in supporting memory and brain function is moderate, but the specific contribution of ginkgoheterosides remains less well characterized. Thus, the rating reflects the overall evidence for the extract, recognizing that ginkgoheterosides are key components but not the sole active ingredients.
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alpha-pinene
amino acids
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anthocyanins
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folate
fruit and vegetable blend (proprietary)
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ginkgo biloba
glycerophosphocholine (GPC)
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Other health conditions supported by Ginkgoheteroside
Alzheimer's DiseaseCirculation (to the brain)
Dementia
Memory and Brain Function