Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Flavonones are a subclass of flavonoids, a group of polyphenolic compounds found abundantly in citrus fruits and some other plants. There is emerging scientific interest in the potential neuroprotective effects of flavonoids, including flavonones, due to their antioxidant, anti-inflammatory, and vasodilatory properties. Several preclinical studies (in vitro and animal models) have suggested that certain flavonones, such as hesperidin and naringenin, may help to reduce oxidative stress and inflammation in the brain, processes implicated in cognitive decline and neurodegenerative diseases. Some small human studies have indicated that acute or chronic intake of citrus juices rich in flavonones can modestly improve certain aspects of cognitive performance or cerebral blood flow in older adults. However, the number of well-designed, large-scale clinical trials in humans is limited, and results are not always consistent. The mechanisms by which flavonones might influence brain function are still being elucidated and may involve modulation of neuronal signaling pathways, enhancement of synaptic plasticity, or indirect vascular effects. Overall, while there is a plausible scientific rationale and some preliminary human data, the strength of the evidence remains moderate at best, and flavonones are not established treatments for memory or brain function. More robust clinical trials are needed to confirm their efficacy and understand the optimal dosage and populations that may benefit.

More about Flavonones (unspecified)
More about Memory and Brain Function

Other ingredients used for Memory and Brain Function

Other health conditions supported by Flavonones (unspecified)

Products containing Flavonones (unspecified)