Evidence supporting the use of: Black Seed
For the health condition: Memory and Brain Function
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Black seed (Nigella sativa), also known as black cumin, has a long history of use in traditional medicine systems, particularly in the Middle East, South Asia, and Africa. Its seeds and oil have been used for a variety of ailments, including those related to memory and cognitive function. Traditional practitioners have attributed "brain tonic" or memory-enhancing properties to black seed, often recommending it in formulas for mental clarity or age-related memory issues. There is some emerging scientific interest in black seed's potential neurological benefits, primarily due to its bioactive compound thymoquinone, which shows antioxidant and anti-inflammatory effects in preclinical studies. A handful of small animal studies and very limited human trials suggest possible protective effects on brain tissue and modest improvements in memory or cognitive performance. However, current scientific evidence is preliminary, often involving small sample sizes, short durations, or lacking rigorous controls. Thus, while there is a robust tradition of using black seed for brain and memory support, scientific validation remains limited and inconclusive at this time.
Other ingredients used for Memory and Brain Function
2'-Fucosyllactoseacai berry
acetyl l-carnitine
algal oil
alpha-pinene
amino acids
anchovies
anthocyanins
ashwagandha
asparagus
astaxanthin
waterhyssop
beet
berry flavor
beta caryophyllene
bifidobacterium longum
bilberry
black currant
black garlic
sesame
black tea
blackberry
blueberry
Indian frankincense
broccoli
caprylic acid
catechins
caterpillar mushroom
chaga mushroom
Chinese salvia root
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
cordyceps
creatine monohydrate
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish protein
folate
fruit and vegetable blend (proprietary)
fruit blend (proprietary)
ginkgo biloba
glycerophosphocholine (GPC)
gooseberry
gotu kola
grape
green tea
guarana
guayusa
hesperetin
huperzine A
inositol
jujube
kale
krill oil
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-carnitine
l-carnosine
l-serine
l-taurine
l-theanine
l-tyrosine
lactobacillus reuteri
lecithin
lion's mane
lutein
luteolin
maca
mackerel
marine lipid
matcha
medium chain triglycerides (MCT)
moringa
muira puama
Acetyl-L-Tyrosine
naringin
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oat
oleic acid
olive
omega-3 fatty acids
ophiopogon root
perilla
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
pine bark
pollen
polygala root
pomegranate
pregnenolone
prolyl endopeptidase (PEP)
pumpkin
pyrroloquinoline disodium salt
quail egg
quercetin
reishi mushroom
resveratrol
rhodiola
rutin
saffron
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
black ginger
specialized pro-resolving mediators (SPMs)
spinach
spirulina
strawberry
sulforaphane glucosinolate
threonic acid
tocotrienols
tomato
trans-pterostilbene
almond fruit
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
velvet bean
vinpocetine
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
suma
jiaogulan
tinospora cordifolia
lingzhi
morus
root tuber
ferulic acid
chrysanthemum
cistanche
lotus seed
royal jelly
terpene lactones
purslane
yerba mate
biota seed
goji berry
algae
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
1,3,7-Trimethylpurine-2,6-dione
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
5-methyltetrahydrofolate glucosamine
7,8-Dihydroxyflavone
Arachidonic Acid
Apigenin
Aronia melanocarpa
Anserine
Alpha glyceryl
Andrographolide
Avocado
Agmatine
Adrafinil
Acetylcholine
Amentoflavone
Agarwood
Acacetin
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Acer Truncatum bunge
Aniracetam
anthocyanosides
Black Seed
Bilobalide
Butylphthalide
Beta-hydroxybutyrate
Breadnut
Blepharis
Beef liver
Baccosides
Bacopin
Baicalein
Basidiomycota
Boswellia
Brahmi
Bacopa
Blue-Green Alage
Bifidobacteria
bacoside
Baicalin
Bird's nest
Centrophenoxine
Camellia sinensis
Centella triterpenes
Chinese Mountain Ant
Cyanobacteria
Carnosine
Catalpol
Chebulic acid
Cod Liver Oil
Codonopsis
Cyanidin
Cruciferous
Centella asiatica
Cinnamic Acid
Chocolate
Chinese Ligustrum berry
Creatine
Catuaba
Convolvulus prostratus
Crocetin
Convolvulus Pluricaulis
Celastrus
Cytidine
cola nut
Canscora
Currant
Carnosic acid
Docosahexaenoic Acid
Danshen
Dendrobium
Decursin
Decursinol
Dibenzo-alpha pyrones
Date
Egg
Elk antler
Emblicanin
Eicosapentaenoic Acid
Glycine
Periwinkle
walnut
yohimbine
Other health conditions supported by Black Seed
AcneAllergies (respiratory)
Alzheimer's Disease
Anxiety
Arthritis
Asthma
Autoimmune Disorders
Blood Poisoning
Bronchitis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Colds (antiviral)
Colds (general)
Colds (prevention)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Congestive Heart Failure
Constipation (adults)
Constipation (children)
Cough (dry)
Cough (general)
Cough (spastic)
Diabetes
Diarrhea
Digestion (poor)
Dyspepsia
Eczema
Epilepsy
Fatigue
Fever
Gastritis
Gingivitis
Hair (loss or thinning)
Headache (general)
Headache (sinus)
Headache (tension)
Heart (weakness)
Hepatitis
Hypertension
Inflammation
Influenza
Insomnia
Liver Detoxification
Lupus
Malaria
Memory and Brain Function
Menopause
Migraine
Nausea and Vomiting