Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin A (commonly administered as vitamin A acetate or retinyl palmitate) is scientifically validated for use in the treatment and support of measles, especially in children. Multiple randomized controlled trials and meta-analyses have demonstrated that vitamin A supplementation significantly reduces morbidity and mortality associated with measles, particularly in populations where vitamin A deficiency is prevalent. The World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) both recommend high-dose vitamin A supplementation for children diagnosed with measles, as it can reduce the risk of severe complications such as pneumonia, diarrhea, and blindness.

The efficacy of vitamin A in measles is attributed to its essential role in maintaining the integrity and function of epithelial tissues, as well as supporting immune responses. Measles infection can deplete vitamin A stores, leading to increased risk of severe disease and death. Large studies, including a landmark trial published in the New England Journal of Medicine (1990), showed that vitamin A supplementation halved the mortality rate in hospitalized children with measles in areas with underlying deficiency. Subsequent reviews and policy statements have reinforced these findings.

Thus, vitamin A is not only traditionally used but is also supported by extensive scientific evidence as a critical adjunct therapy for measles, especially in children or in settings where vitamin A deficiency is common.

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