Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Senna occidentalis (formerly known as Cassia occidentalis) has been traditionally used in various regions, particularly in Africa and Asia, as part of ethnobotanical remedies for malaria and related febrile illnesses. Documentation exists in ethnopharmacological surveys describing decoctions of the leaves, roots, or seeds being administered for fevers presumed to be malaria. However, scientific validation for its efficacy is limited. Some in vitro studies have assessed crude extracts of Senna occidentalis for antiplasmodial activity, but results have generally shown only mild to moderate inhibition of Plasmodium falciparum growth, and active compounds have not been well characterized. Moreover, toxicological concerns exist, as the plant contains anthraquinones and other compounds with known hepatotoxic and nephrotoxic potential. Clinical studies in humans are lacking. Therefore, its use for malaria is primarily justified by traditional and ethnomedical practices rather than rigorous scientific evidence, and caution is warranted due to potential toxicity. Current antimalarial guidelines do not recommend Senna occidentalis as a treatment.

More about Senna occidentalis
More about Malaria

Other ingredients used for Malaria

Other health conditions supported by Senna occidentalis

Products containing Senna occidentalis