Synopsis

Source of validity: Traditional
Rating (out of 5): 1

The blackboard tree (Alstonia scholaris) has a longstanding place in traditional medicine systems, particularly in South and Southeast Asia. Its bark and other parts have been used in Ayurvedic and folk medicine for a variety of ailments, including fever and symptoms associated with malaria. The rationale for its use stems from its purported antipyretic (fever-reducing) and tonic properties rather than direct antimalarial effects. Historical texts and ethnobotanical surveys document its use as part of herbal remedies for feverish illnesses, which in malaria-endemic regions were often attributed to malaria.

Though there are some preliminary phytochemical studies indicating the presence of alkaloids and other compounds in Alstonia scholaris with potential biological activity, robust scientific evidence specifically validating its efficacy against Plasmodium parasites (the causative agents of malaria) is lacking. Clinical trials or well-controlled in vitro studies directly demonstrating antimalarial effects are minimal or absent. Thus, while its historical use is well established, the evidence base supporting its use for malaria is weak, and it should not be considered a substitute for proven antimalarial therapies. Further research may be warranted, but at present, its application is primarily justified by tradition rather than modern scientific validation.

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