Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cyanidin is an anthocyanin flavonoid found in various fruits and vegetables, such as berries and red cabbage. Its use in supporting or treating macular degeneration is primarily based on emerging scientific research rather than long-standing traditional use. Preclinical studies have shown that cyanidin and other anthocyanins possess antioxidant and anti-inflammatory properties, which are believed to help protect retinal cells from oxidative stress—a key factor in the development of age-related macular degeneration (AMD). Several in vitro and animal studies indicate that anthocyanins can reduce oxidative damage in retinal tissues and may improve retinal function. For example, a 2017 study in the journal Molecular Vision demonstrated that cyanidin-3-glucoside could protect cultured retinal pigment epithelial cells from oxidative injury.

However, direct clinical evidence in humans is limited. Most available human studies on anthocyanins and eye health use mixed extracts or focus on general visual function rather than specifically on AMD. While some observational studies suggest a link between higher dietary intake of anthocyanins and reduced risk of AMD, these are not sufficient to establish causality. Overall, the scientific evidence supporting cyanidin for macular degeneration is promising but preliminary, warranting further clinical trials to confirm efficacy and optimal dosing.

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